1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-17
  5. IL-17D

Interleukin-17D (IL-17D) belongs to the IL-17 cytokine family. IL-17D is highly secreted by fibrosarcoma tumor cells[1]. IL-17D is highly expressed in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas, while it is expressed at low levels in bone marrow, fetal liver, kidney, leukocytes, liver, lymph nodes, placenta, spleen, thymus, and tonsils[2]. IL-17D stimulates the production of IL-6, IL-8, and GM-CSF. IL-17D also induces myeloid growth factors and chemokines. IL-17D stimulates local infiltration and proliferation of leukocytes[2]. IL-17D regulates protective immunity during intracellular bacteria and virus infection via regulating CD8 T cells[1]. IL-17D plays multiple roles in autoimmune disease and is a potential target for tumor immunotherapy[2].

Cat. No. Product Name / Synonyms Species Source
  • HY-P70587
    IL-17D Protein, Human

    Interleukin-17D; IL-17D; IL17D

    Human E. coli
    IL-17D protein acts as a potent inducer, effectively triggering endothelial cells to express key inflammatory mediators such as IL6, CXCL8/IL8, and CSF2/GM-CSF. The ability of this cytokine to stimulate the production of pro-inflammatory signals emphasizes its importance in orchestrating immune responses, particularly in the context of endothelial cell activation. IL-17D Protein, Human is the recombinant human-derived IL-17D protein, expressed by E. coli , with tag free. The total length of IL-17D Protein, Human is 185 a.a., with molecular weight of ~20.0 kDa.
  • HY-P700106AF
    Animal-Free IL-17D Protein, Human (His)

    Interleukin-17D; IL-17D; IL17D

    Human E. coli
    IL-17D protein acts as a potent inducer, effectively triggering endothelial cells to express key inflammatory mediators such as IL6, CXCL8/IL8, and CSF2/GM-CSF. The ability of this cytokine to stimulate the production of pro-inflammatory signals emphasizes its importance in orchestrating immune responses, particularly in the context of endothelial cell activation. Animal-Free IL-17D Protein, Human (His) is the recombinant human-derived animal-FreeIL-17D protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free IL-17D Protein, Human (His) is 185 a.a., with molecular weight of ~21.00 kDa.
Cat. No. Product Name Effect Purity