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Cat. No.: HY-100815

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(R)-AMPA

(R)-AMPA is an inactive AMPA receptor ligand that inhibits the release of excitatory amino acids from neurons. (R)-AMPA is inactive in experiments that enhance the release of [3H]D-aspartate induced by electrical stimulation. (R)-AMPA is inhibited by competitive and noncompetitive AMPA receptor selective antagonists in response to AMPA and glutamate.

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CAS No.: 83654-13-1
Formule: C₇H₁₀N₂O₄
Masse moléculaire:186.17

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(R)-AMPA Chemical Structure

CAS No.: 83654-13-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
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- Cellular Effect
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Activité biologique

Description

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Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	>1000 μM Compound: (R)-7	Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2 Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2	[PMID: 8759641]
CHO	EC₅₀	>1000 μM Compound: (R)-7	Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6 Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6	[PMID: 8759641]
CHO	EC₅₀	>1000 μM Compound: (R)-7	Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alpha Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alpha	[PMID: 8759641]

Chemical Information

CAS No. 83654-13-1
Masse moléculaire 186.17
Formule C₇H₁₀N₂O₄
SMILES

O=C1C(C[C@@H](N)C(O)=O)=C(C)ON1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Evidence for a role of presynaptic AMPA receptors in the control of neuronal glutamate release in the rat forebrain

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(R)-AMPA

Voir tous les produits spécifiques à Isoform iGluR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(R)-AMPA Related Classifications

HY-100815 Related Classifications