56 Results for "

hyper-responsiveness

" in MedChemExpress (MCE) Product Catalog:
Products (56)

56 Results for "hyper-responsiveness" in MCE Product Catalog:

28
28 Publications Verification
Cat. No.: HY-P70568
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
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26
26 Cited Publications
Cat. No.: HY-P70460
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
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17
17 Cited Publications
Cat. No.: HY-P72795
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
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9
9 Cited Publications
Cat. No.: HY-P7033
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Source:  
CHO
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8
8 Cited Publications
Cat. No.: HY-P1098
CAS No.: 151988-33-9
Target:  

Annexin A NF-κB

Domaines de recherche:  

Inflammation/Immunology

Ac2-26 is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ameliorates lung ischemia-reperfusion injury. Ac2-26 also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .
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8
8 Cited Publications
Cat. No.: HY-P1098A
Target:  

Annexin A NF-κB

Domaines de recherche:  

Inflammation/Immunology

Ac2-26 TFA is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ameliorates lung ischemia-reperfusion injury. Ac2-26 also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .
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8
8 Cited Publications
Cat. No.: HY-P1098B
Target:  

IKK

Domaines de recherche:  

Inflammation/Immunology

Ac2-26 ammonium is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 ammonium induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ammonium ameliorates lung ischemia-reperfusion injury. Ac2-26 ammonium also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .
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6
6 Cited Publications
Cat. No.: HY-A0083
CAS No.: 62-51-1
Synonyms: Acetyl-β-methylcholine chloride
Target:  

mAChR

Domaines de recherche:  

Others

Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates .
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5
5 Cited Publications
Cat. No.: HY-W250978
CAS No.: 9006-59-1
Ovalbumins are the major proteins in egg white. Ovalbumins act as an allergen and inducer, and can be applied to mouse models of allergic diseases. Ovalbumins can induce allergic rhinitis in mice via sensitization and nasal challenge. Ovalbumins can be used to establish asthma models.
Ovalbumin, low endotoxin (HY-W250978A) is recommended for model establishment .
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3
3 Cited Publications
Cat. No.: HY-P7076A
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-N0668
CAS No.: 64849-39-4
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
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1
1 Cited Publications
Cat. No.: HY-12545
CAS No.: 85079-48-7
Synonyms: PbTx-3
Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na + channel activator and has multiple active centers (A-ring lactone, C-42 of R side chain) . Brevetoxin-3 (PbTx-3) has a high affinity to site 5 of the voltage-sensitive Na + channels, inhibits the inactivation of Na + channels and prolongs the mean open time of these channels. Brevetoxin-3 (PbTx-3) repeated exposures can lead to prolonged airway hyperresponsiveness (AHR) and lung inflammation .
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1
1 Cited Publications
Cat. No.: HY-P7099
Pureté:  ≥ 98%, as determined by reducing SDS-PAGE.;≥ 98%, as determined by HPLC.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Rat
Source:  
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1
1 Cited Publications
Cat. No.: HY-P70779
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P72595
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
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Cat. No.: HY-N0825
CAS No.: 495-31-8
Nodakenin is a major coumarin glucoside in the root of Angelica decusiva. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM .
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Cat. No.: HY-19393
CAS No.: 444659-43-2
SCH 351591 is a highly selective, orally active PDE4 inhibitor, with IC50 values of 58 nM and 153 nM in humans and rats, respectively. SCH 351591 effectively inhibits pathological processes such as cytokine production, eosinophilia, airway hyperresponsiveness and bronchospasm. SCH 351591 also induces microvascular injury, activates mast cells and endothelial cells, and causes increases in serum histamine and various inflammatory factors, leading to early vascular damage. SCH 351591 has been widely used in studies related to asthma, chronic obstructive pulmonary disease and drug-induced vascular injury .
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Cat. No.: HY-N0081
CAS No.: 73069-25-7
(±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases .
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Cat. No.: HY-149478
CAS No.: 2238820-43-2
Pureté:  99.54%
Domaines de recherche:  

Inflammation/Immunology

JT002 is an orally active and selective NLRP3 inflammasome assembly inhibitor. JT002 reduces NLRP3-dependent proinflammatory cytokine (such as IL-1β, IL-1α, IL-18) production and pyroptosis. JT002 blocks NLRP3 inflammasome complex formation. JT002 reduces airway hyperresponsiveness and airway neutrophilia in mice. JT002 can be used for the study of a variety of inflammatory diseases, such as Muckle-Wells syndrome (MWS) .
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Cat. No.: HY-P99193
CAS No.: 909875-08-7
Synonyms: MEDI-528

Target:  

Interleukin Related

Domaines de recherche:  

Inflammation/Immunology

Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways .
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