BIO-2007817
Based on 1 Customer Validation
BIO-2007817 is a Parkin positive allosteric modulators (PAMs). BIO-2007817 enhances the activity of wildtype Parkin. BIO-2007817 stimulates Parkin (an E3 ligase)autoubiquitination and induces the appearance of monoubiquitinated forms of Miro1 (EC50: 0.17 μM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.35%
- Formel: C32H36N6O3
- Molecular Weight:552.67
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
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Appearance Solid
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Molecular Weight 552.67
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Formel C32H36N6O3
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Color White to off-white
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SMILES
CO[C@@H](C1=CN(N=C1)C)C(N2CC3=C(C=NN3C[C@H]2C(C)C)C4=CC=C(C=C4)C(N5CCCC6=C5C=CC=C6)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (90.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.8094 mL | 9.0470 mL | 18.0940 mL | 45.2350 mL |
| 5 mM | 0.3619 mL | 1.8094 mL | 3.6188 mL | 9.0470 mL | |
| 10 mM | 0.1809 mL | 0.9047 mL | 1.8094 mL | 4.5235 mL | |
| 15 mM | 0.1206 mL | 0.6031 mL | 1.2063 mL | 3.0157 mL | |
| 20 mM | 0.0905 mL | 0.4523 mL | 0.9047 mL | 2.2617 mL | |
| 25 mM | 0.0724 mL | 0.3619 mL | 0.7238 mL | 1.8094 mL | |
| 30 mM | 0.0603 mL | 0.3016 mL | 0.6031 mL | 1.5078 mL | |
| 40 mM | 0.0452 mL | 0.2262 mL | 0.4523 mL | 1.1309 mL | |
| 50 mM | 0.0362 mL | 0.1809 mL | 0.3619 mL | 0.9047 mL | |
| 60 mM | 0.0302 mL | 0.1508 mL | 0.3016 mL | 0.7539 mL | |
| 80 mM | 0.0226 mL | 0.1131 mL | 0.2262 mL | 0.5654 mL |
BIO-2007817 Related Classifications
HY-169329 Related Classifications
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