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Art. -Nr.: HY-122552

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Chrysotobibenzyl

Chrysotobibenzyl can be isolated from stem of Dendrobium pulchellum. Chrysotobibenzyl inhibits lung cancer cell (H460 and H292) migration, invasion, filopodia formation via Cav-1, integrins β1, β3, and αν, and EMT suppressions. Chrysotobibenzyl also sensitizes lung cancer cell death mediated by Cisplatin (HY-17394).

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CAS. Nr.: 108853-09-4
Formel: C₁₉H₂₄O₅
Molecular Weight:332.39

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Chrysotobibenzyl Chemical Structure

CAS. Nr.: 108853-09-4

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Beschreibung

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Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	15 μM Compound: 3a	Compound was tested for inhibition of cell growth of A-549 cells Compound was tested for inhibition of cell growth of A-549 cells	10.1016/0960-894X(95)00008-H
HT-29	IC₅₀	15 μM Compound: 3a	Compound was tested for inhibition of cell growth of HT-29 cells Compound was tested for inhibition of cell growth of HT-29 cells	10.1016/0960-894X(95)00008-H
L1210	IC₅₀	20 μM Compound: 5	Cytotoxicity against mouse L1210 cells after 24 hrs Cytotoxicity against mouse L1210 cells after 24 hrs	[PMID: 3404149]
NCI-H23	IC₅₀	252.24 μM Compound: 34	Anti-cancer activity against human NCI-H23 cells Anti-cancer activity against human NCI-H23 cells	[PMID: 32711292]
P388	IC₅₀	15 μM Compound: 3a	Compound was tested for inhibition of cell growth of P-388 cells Compound was tested for inhibition of cell growth of P-388 cells	10.1016/0960-894X(95)00008-H
RAW	IC₅₀	48.2 μM Compound: 5	Inhibition of LPS and TNF-alpha-activated NO production in murine RAW 264.7 cells Inhibition of LPS and TNF-alpha-activated NO production in murine RAW 264.7 cells	[PMID: 17253844]

Chemical Information

CAS. Nr. 108853-09-4
Molecular Weight 332.39
Formel C₁₉H₂₄O₅
SMILES

COC1=C(OC)C(OC)=CC(CCC2=CC=C(OC)C(OC)=C2)=C1
Structure Classification
- Others
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Petpiroon N, et al. Chrysotobibenzyl inhibition of lung cancer cell migration through Caveolin-1-dependent mediation of the integrin switch and the sensitization of lung cancer cells to cisplatin-mediated apoptosis. Phytomedicine. 2019 May;58:152888. [Content Brief]

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Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chrysotobibenzyl

Alle Integrin Isoform-spezifische Produkte anzeigen

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Chrysotobibenzyl Related Classifications

HY-122552 Related Classifications