Ces1d - carboxylesterase 1D Gene

Also Known as TGH; Ces3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104158

Summary

Enables sterol esterase activity and triglyceride Lipase activity. Involved in acylglycerol catabolic process. Acts upstream of or within several processes, including cellular lipid catabolic process; temperature homeostasis; and very-low-density lipoprotein particle assembly. Located in cytosol; endoplasmic reticulum lumen; and lipid droplet. Is expressed in several structures, including cochlear duct; gut; liver; nose; and respiratory system. Orthologous to human CES1 (carboxylesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ces1d Products (2)

mRNA Protein Name
NM_053200.2 NP_444430.2 carboxylesterase 1D precursor
NM_053200.2 NP_444430.2 carboxylesterase 1D precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables carboxylesterase activity IMP
IMP: Inferred from mutant phenotype
20197051 MGI
enables carboxylic ester hydrolase activity IDA
IDA: Inferred from direct assay
15220344 MGI
enables sterol ester esterase activity IDA
IDA: Inferred from direct assay
15220344 MGI
enables triacylglycerol lipase activity IDA
IDA: Inferred from direct assay
15220344 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in acylglycerol catabolic process IDA
IDA: Inferred from direct assay
15220344 MGI
acts upstream of or within cellular response to cold IMP
IMP: Inferred from mutant phenotype
30862682 MGI
acts upstream of or within circadian temperature homeostasis IMP
IMP: Inferred from mutant phenotype
30862682 MGI
acts upstream of or within cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
30862682 MGI
acts upstream of or within cytosolic lipolysis IMP
IMP: Inferred from mutant phenotype
30862682 MGI
acts upstream of or within lipid catabolic process IDA
IDA: Inferred from direct assay
11470237 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
30862682 MGI
acts upstream of or within short-chain fatty acid catabolic process IDA
IDA: Inferred from direct assay
16804080 MGI
acts upstream of or within very-low-density lipoprotein particle assembly IMP
IMP: Inferred from mutant phenotype
20197051 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cytosol IDA
IDA: Inferred from direct assay
15220344 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
30862682 MGI
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
15220344 MGI
located in lipid droplet IDA
IDA: Inferred from direct assay
15220344 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carboxylesterase 1D

  • FAEE synthase

  • carboxylesterase 3

  • fatty acid ethyl ester synthase

  • triacylglycerol hydrolase

Recombinant Ces1d Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P70088 CES3/CES1D Protein, Mouse (HEK293, His) Q8VCT4 (Y19-E561) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-120602 WWL229 Inhibitor 99.49% Unkown