Gilvocarcin M
Gilvocarcin M is an antibiotic and can be isolated from S. gilvotanareus. Gilvocarcin M is active against S. aureus at a concentration of 32 µg/ml and inhibits growth of KB cells with the IC50 of 0.52 µg/ml. Gilvocarcin M intercalates into bacteriophage PM2 DNA.
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- CAS. Nr.: 77879-89-1
- Formel: C26H26O9
- Molecular Weight:482.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 77879-89-1
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Molecular Weight 482.48
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Formel C26H26O9
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SMILES
O=C1C2=CC(C)=CC(OC)=C2C3=CC(OC)=C4C(O)=CC=C([C@@H]5[C@@H]([C@H]([C@H]([C@@H](C)O)O5)O)O)C4=C3O1
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Structure Classification
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Initial Source
Streptomyces sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Nakano H,et al. Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo). 1981;34(3):266-270. [Content Brief]
[2]. Morimoto M, et al. Gilvocarcins, new antitumor antibiotics. 3. Antitumor activity. J Antibiot (Tokyo). 1981;34(6):701-707. [Content Brief]
[3]. Tomita F, et al. Gilvocarcins, new antitumor antibiotics. 4. Mode of action. J Antibiot (Tokyo). 1982 Aug;35(8):1038-41. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)