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Art. -Nr.: HY-185425

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SM6.1-azide

SM6.1-azide is a reactant containing an azide group, which can be used in copper-catalyzed azide-alkyne cycloaddition click reactions. SM6.1-azide facilitates the synthesis of trivalent targeted ligand-siRNA conjugates. SM6.1-azide undergoes click chemistry reactions with alkyne-modified oligonucleotides.

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CAS. Nr.: 2320477-40-3
Formel: C₄₁H₅₁N₇O₉
Molecular Weight:785.89

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

SM6.1-azide Chemical Structure

CAS. Nr.: 2320477-40-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

SM6.1-azide (3-18.5 equivalents relative to oligo; 0.5-2.5 h) undergoes copper-catalyzed click conjugation with alkyne-modified oligonucleotide, with optimized conditions producing crude yields up to 85.34% and crude purities up to 79.58% while minimizing 2-branch impurities^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2320477-40-3
Molecular Weight 785.89
Formel C₄₁H₅₁N₇O₉
SMILES

[N-]=[N+]=NCCOCCOCCOCCOCCOC1=CC=C(C2=CC=C(C=C2)[C@H](CC(O)=O)NC(CNC(CCCNC3=CC(C)=CC=N3)=O)=O)C4=C1C=CC=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Pan F, et al. Model-Assisted Process Optimization for Trivalent Ligand-siRNA Conjugation via CuAAC Click Chemistry. ACS Omega. 2025 Oct 27;10(43):52010-52017. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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