Others

4-Aza-Oleanolic acid methyl ester is a triterpenic derivative.

CEP-28122 mesylate hydrochloride, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC₅₀ value of 1.9 nM. CEP-28122 mesylate hydrochloride has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate hydrochloride has good pharmacodynamic and pharmacokinetic activity. CEP-28122 mesylate hydrochloride can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells.

AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a K_D of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope.

41-O-Demethylrapamycin is a metabolite of Rapamycin (HY-10219) produced by Bacillus megaterium.

18-Oxooleate is a nucleoside metabolite.

MRC71 is a TRIMTAC degrader that recruits endogenous TRIM21 E3 ligase at one end and covalently binds to HaloTag-fusion target proteins at the other end. MRC71 selectively degrades oligomeric CAV1- and Cavin1-mEGFP-Halo, but not monomeric mEGFP-Halo, and exhibits a typical concentration-dependent degradation profile with a hook effect. MRC71 can be used to verify TRIMTAC ternary complex formation and state-selective degradation in cells.

17-Hydroxylinolenic acid is a nucleoside metabolite.

9(S)-HPETE is an intermediate in the biosynthesis of dictyopterene A in the freshwater diatom Gomphonema parvulum.

9,10,18-Trihydroxystearic acid is a C18 family of hydroxy acid.

9,10-Epoxy13-hydroxy-11-octadecenoic acid is a fatty acid.

(5Z,13E)-6,9Alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate (15-Dehydro-prostaglandin I2) is an analogue of prostaglandin I2.

3-Indoleglycolaldehyde, a bacterial metabolite, is a plant growth promoter.

Vulpecholic acid is a nucleoside metabolite.

4α-Methylfecosterol is an unsaponifiable lipid.

11,14,15-THETA (11,14,15-Trihydroxyeicosatrienoic acid) is a nucleoside metabolite.

15H-11,12-EETA is a nucleoside metabolite.

9,10-Epoxy-18-hydroxyoctadecanoic acid exists as a component of cutin in plants, and is an essential polymer that protects plants by minimizing the influence of pathogens by waterproofing the leaves and fruits of plants.

9-Hydroxy-12-oxo-15(Z)-octadecenoic acid is a metabolite of octadecenoic acid in free fatty acids.

(R)-2-Hydroxy-α-linolenic acid is a nucleoside metabolite.

22-Oxodocosanoic acid is a nucleoside metabolite.