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Cat. No.: HY-180158

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Antitrypanosomal agent 28

Antitrypanosomal agent 28 (Compound 2a) is a trypanocidal agent. Antitrypanosomal agent 28 effectively inhibits Trypanosoma cruzi by inducing the generation of ROS and mitochondrial damage, with an IC₅₀ of 49.4 μM. Antitrypanosomal agent 28 exhibits broad-spectrum anti-tumor activity against various tumor cell lines, especially being sensitive to leukemia, colon cancer, and breast cancer. Antitrypanosomal agent 28 can be used for research on anti-cancer and anti-trypanosome activities.

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CAS No.: 2413738-47-1
Formule: C₂₇H₂₁NO
Masse moléculaire:375.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Antitrypanosomal agent 28 Chemical Structure

CAS No.: 2413738-47-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

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Chemical Information

CAS No. 2413738-47-1
Masse moléculaire 375.46
Formule C₂₇H₂₁NO
SMILES

CC1=NC2=CC=CC=C2C(/C=C/C3=CC=CC=C3)=C1C(/C=C/C4=CC=CC=C4)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Rodríguez D, et al. Quinolinyl-appended chalcones as promising antiproliferative and trypanocidal agents: Synthesis, biological profiling, and further transformation into novel benzo[f]pyrazolo[5,1-a][2,7]naphthyridine and quinoline-pyrido[2,3-d]pyrimidin-2,4-dione hybrids. Bioorg Chem. 2025 Dec 2;168:109306. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Antitrypanosomal agent 28

Voir tous les produits spécifiques à Isoform Parasite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Antitrypanosomal agent 28 Related Classifications

HY-180158 Related Classifications