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Cat. No.: HY-P2569

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Malformin A1

Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9.

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CAS No.: 3022-92-2
Formule: C₂₃H₃₉N₅O₅S₂
Masse moléculaire:529.72

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Please store the product under the recommended conditions in the Certificate of Analysis.

Malformin A1 Chemical Structure

CAS No.: 3022-92-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
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Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
U-937	IC₅₀	0.76 μM Compound: 1; synthetic	Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27680590]
U-937	IC₅₀	0.8 μM Compound: 1; natural	Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27680590]

Chemical Information

CAS No. 3022-92-2
Masse moléculaire 529.72
Formule C₂₃H₃₉N₅O₅S₂
Sequence Shortening

CCVLI (Disulfide bridge:Cys1-Cys2)
Structure Classification
- Others
Initial Source
- Endogenous metabolite
- Human Gut Microbiota Metabolites
- Microorganisms
Aspergillus niger
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sun-Young Park, et al. Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway. Int J Oncol. 2017 Sep;51(3):959-966. [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Malformin A1

Coenzyme Q2

3BDO

Delphinidin chloride

Gingerenone A

Napyradiomycin A1

9-β-D-Arabinofuranosylguanine

PHY34

1,7-Dimethyluric acid

QN523

O-Methylsterigmatocystin

Delphinidin chloride (Standard)

Gingerenone A (Standard)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Bioz

Malformin A1

Coenzyme Q2

3BDO

Delphinidin chloride

Gingerenone A

Napyradiomycin A1

9-β-D-Arabinofuranosylguanine

PHY34

1,7-Dimethyluric acid

QN523

O-Methylsterigmatocystin

Delphinidin chloride (Standard)

Gingerenone A (Standard)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Malformin A1 Related Classifications

HY-P2569 Related Classifications

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