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Cat. No.: HY-121738

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TC AC 28

TC AC 28 is a high-affinity BET bromodomain ligand with K_d values of 40, 800 nM for Brd2(2), Brd2(1), respectively.

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CAS No.: 1809296-92-1
Formule: C₂₃H₂₁N₅O₃
Masse moléculaire:415.44

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

TC AC 28 Chemical Structure

CAS No.: 1809296-92-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Description
- IC₅₀ & Target
Chemical Information
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Description

TC AC 28 is a high-affinity BET bromodomain ligand with K_d values of 40, 800 nM for Brd2(2), Brd2(1), respectively^[1].

IC₅₀ & Target^[1]

BRD2(1)

40 nM (Kd)

BRD2(2)

800 nM (EC₅₀)

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Chemical Information

CAS No. 1809296-92-1
Masse moléculaire 415.44
Formule C₂₃H₂₁N₅O₃
SMILES

COC(CC1N=C(C2=C3C=CNC3=CC=C2)C4=CC(OC)=CC=C4N5C(C)=NN=C15)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Khan R, et al. Gram-Scale Laboratory Synthesis of TC AC 28, a High-Affinity BET Bromodomain Ligand. ACS Omega. 2017 Aug 8;2(8):4328-4332. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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TC AC 28

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

TC AC 28 Related Classifications

HY-121738 Related Classifications