GS-8873 TFA
GS-8873 TFA is the TFA salt form of GS-8873 (HY-145713). GS-8873 TFA is an orally active inhibitor for the production of hepatitis B virus (HBV) surface antigen (HBsAg) with an EC50 of 4 nM. GS-8873 TFA exhibits good pharmacokinetic characters in rats and metabolic stability in human hepatocytes. GS-8873 TFA causes neurofunctional deficits in rats and cynomolgus monkeys.
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- CAS. Nr.: 2241575-60-8
- Formel: C26H31F3N2O8
- Molecular Weight:556.53
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 2241575-60-8
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Molecular Weight 556.53
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Formel C26H31F3N2O8
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SMILES
OC(C(F)(F)F)=O.COCC1=C(OCCCOC)C=C([C@]2([H])N(C(C)(CC2)C)N3C4=CC(C(C(O)=O)=C3)=O)C4=C1
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Synonyms
HBV-IN-19 TFA
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)