Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4563)
Related Products (4563)
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L-Lactic acid sodium
0 ImagesSynonyms: (S)-2-Hydroxypropanoic acid sodiumL-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity.
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Fmoc-Arg(Pbf)-OH
0 ImagesFmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis).
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tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate
![tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate](https://file.medchemexpress.com/product_pic/hy-30536.gif "Click to View tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate Product Detail")
0 Imagestert-Butyl 3,9-diazaspiroundecane-3-carboxylate is a 3,9-diazaspiroundecane-based building block and precursor for synthesizing γ-aminobutyric acid type A (GABAA) receptor antagonists.
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4-Aminobenzyl alcohol
0 Images4-Aminobenzyl alcohol is a self-eliminating linker. 4-Aminobenzyl alcohol can be used to synthesize the fluorescent probe MB-Van1 targeting Vanin-1.
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Pteroic acid
0 ImagesPteroic acid is a precursor to significant compounds like Folic acid (HY-16637) and Vitamin B12 (HY-B0315). Pteroic acid facilitates the examination of how different compounds influence cell growth and development.
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5-Bromo-L-tryptophan
0 Images5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research.
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2-Tetralone
0 Images2-Tetralone (Beta-Tetralone) is a cyclic bis-sterically hindered ketone and a ketone derivative of tetrafluoramine. 2-Tetralone exhibits anticancer activity, inhibits cell migration and proliferation, and induces apoptosis. 2-Tetralone is often used as a pharmaceutical intermediate in studies related to organic synthesis.
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HPMC (Viscosity:11250-21000mPa.s)
0 ImagesSynonyms: Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
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UDP-glucuronic acid trisodium
0 ImagesSynonyms: Uridine 5'-diphosphoglucuronic acid trisodium saltUDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
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(R)-5,7-Difluorochroman-4-ol
0 Images(R)-5,7-Difluorochroman-4-ol is a drug intermediate for synthesis of various active compounds.
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Sirpiglenastat
0 ImagesSynonyms: DRP-104Sirpiglenastat (DRP-104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response.
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DBU
0 ImagesDBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic sterically hindered amidine with strong basicity, which possesses multiple properties such as nucleophilicity and coordination ability. DBU is prone to hydrolysis and can undergo addition, substitution, cyclization and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst.
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Exatecan Intermediate 2
0 ImagesExatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers.
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tert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate
![tert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate](https://file.medchemexpress.com/product_pic/hy-w054424.gif "Click to View tert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate Product Detail")
0 Imagestert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl) carbamate is a pharmaceutical intermediate used in the synthesis of various active compounds, such as for the preparation of tetrazole-based eIF2B activators.
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4-Chloro-6,7-dimethoxyquinoline
0 ImagesSynonyms: Oro-6,7-dimethoxyquinol4-Chloro-6,7-dimethoxyquinoline (Oro-6,7-dimethoxyquinol) is a drug intermediate for synthesis of various active compounds.
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tBu2bpy
0 ImagestBu2bpy is a bidentate nitrogen ligand that coordinates with Pt (II) and Pt (IV) to form functional complexes. The tBu2bpy Pt (II) bis-crown ether complex selectively recognizes Mg2+ and Zn2+; both ions significantly enhance the fluorescence of the complex and cause a blue shift of the absorption peak. Its six-coordinate Pt (IV) complex [Pt (X)2Me2 (tBu2bpy)] inhibits the proliferation of tumor cells. tBu2bpy Pt (IV) complexes bind to DNA through multiple interactions including partial intercalation, groove binding, and electrostatic interaction, and can competitively displace ethidium bromide and covalently bind to purine nucleotides. tBu2bpy can be used in relevant research in fields such as organic synthesis.
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6-Chloropyrimidine-4-carboxylic acid
0 Images6-Chloropyrimidine-4-carboxylic acid is a drug intermediate for synthesis of various active compounds.
