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  4. L-Lactic acid sodium

L-Lactic acid sodium  (Synonyms: (S)-2-Hydroxypropanoic acid sodium)

Cat. No.: HY-W040233 Purity: 98.54%
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SDS
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L-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity.

For research use only. We do not sell to patients.

CAS No. : 867-56-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
25 mg In-stock
50 mg In-stock
100 mg In-stock
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Customer Review

Based on 14 publication(s) in Google Scholar

Other Forms of L-Lactic acid sodium:

L-Lactic acid sodium Related Antibodies

Top Publications Citing Use of Products

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098.  [Abstract]

    Lactate (L-Lactic acid; 24 h) TU668 cells, the expression levels of hub genes were quantified by PCR.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098.  [Abstract]

    Lactate (L-Lactic acid; 15 mM; 24, 48, 72 h) cell viability was assessed using the CCK-8 assay in TU686 cells.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Aug 24;323(Pt 1):147098.  [Abstract]

    Lactate (L-Lactic acid; 15 mM; 0, 48 h), cell migration capacity was evaluated via a scratch wound healing assay in TU686 cells.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Apr 9;44(4):115545.  [Abstract]

    HT1376 and RT112 cells were treated with lactate (10 mM)/oxamate (10 mM) for 24 h. Then, the cells were harvested for lactic acid content detection analysis.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Apr 9;44(4):115545.  [Abstract]

    HT1376 and RT112 cells were treated with lactate (10 mM)/oxamate (10 mM) for 24 h. Then, the cells were harvested for lactic acid content detection analysis.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Cell Rep. 2025 Apr 9;44(4):115545.  [Abstract]

    HT1376 and RT112 cells were treated with the lactate (10 mM) for 48 h then treated with continuous doses of EV for 24 h and harvested for CCK-8 assays to measure the IC50 values of EV.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Mar;11(10):e2304761.  [Abstract]

    Evaluation of the viability of BMSCs cultured on microspheres with or without lactate (L-Lactic acid; 6 mM) for 24 h. Fluorescence images of the live/dead assays of BMSCs cultured on microspheres with or without lactate for 24 h.

    L-Lactic acid sodium purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2022 Dec 1;222(Pt B):2225-2243.  [Abstract]

    Assessed by WB, extracellular lactate (L-Lactic acid) treatment (10 mM, 72 h) significantly increased VE-cadherin and p-EphA2 (Ser897) expressions, which could be reversed by MCT1 silencing PC-3 cells.

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    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    L-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity[1][2][3].

    In Vitro

    L-Lactic Acid (24-48 h) sodium secreted from gastric mucosal cells enhances growth of Helicobacter pylori[1].
    L-Lactic Acid (48 h) sodium shows antiproliferative activity against human A549 and MRC5 cells, with IC50 of 26.6 μM and 23.93 μM[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    L-Lactic acid sodium Related Antibodies
    In Vivo

    L-Lactic acid (25-50 mg/kg, i.p., twice, 4 days apart) sodium dose-dependently enhances swimming endurance in mice[3].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Molecular Weight

    112.06

    Formula

    C3H5NaO3
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    [C@@H](C(O)=O)(C)O.[Na]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    H2O : ≥ 100 mg/mL (892.38 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 8.9238 mL 44.6190 mL 89.2379 mL
    5 mM 1.7848 mL 8.9238 mL 17.8476 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 98.54%

    SDS (393 KB)

    COA (251 KB) HNMR (108 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 8.9238 mL 44.6190 mL 89.2379 mL 223.0948 mL
    5 mM 1.7848 mL 8.9238 mL 17.8476 mL 44.6190 mL
    10 mM 0.8924 mL 4.4619 mL 8.9238 mL 22.3095 mL
    15 mM 0.5949 mL 2.9746 mL 5.9492 mL 14.8730 mL
    20 mM 0.4462 mL 2.2309 mL 4.4619 mL 11.1547 mL
    25 mM 0.3570 mL 1.7848 mL 3.5695 mL 8.9238 mL
    30 mM 0.2975 mL 1.4873 mL 2.9746 mL 7.4365 mL
    40 mM 0.2231 mL 1.1155 mL 2.2309 mL 5.5774 mL
    50 mM 0.1785 mL 0.8924 mL 1.7848 mL 4.4619 mL
    60 mM 0.1487 mL 0.7436 mL 1.4873 mL 3.7182 mL
    80 mM 0.1115 mL 0.5577 mL 1.1155 mL 2.7887 mL
    100 mM 0.0892 mL 0.4462 mL 0.8924 mL 2.2309 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    L-Lactic acid sodium Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-Lactic acid867-56-1(S)-2-Hydroxypropanoic acidDrug IntermediateEnvironmental PollutantsBacterialAntibioticEndogenous MetaboliteDrug IintermediateEnvironmental ContaminantsPoly-lactic acidAntiproliferative.Inhibitorinhibitorinhibit

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