(RS)-PPG (Standard)
(RS)-PPG (Standard) is the analytical standard of (RS)-PPG (HY-107514). This product is intended for research and analytical applications. (RS)-PPG is a potent and selective agonist for group III mGluRs. The EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively. Anticonvulsive and neuroprotective activity.
For research use only. We do not sell to patients.
- CAS No.: 120667-15-4
- Formula: C8H10NO5P
- Molecular Weight:231.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 5.2 μM (hmGluR4a), 4.7 μM (hmGluR6), 185 μM (hmGluR7b), and 0.2 μM (hmGluR8a)[1]
Chemical Information
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CAS No. 120667-15-4
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Molecular Weight 231.14
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Formula C8H10NO5P
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SMILES
O=C(O)C(N)C1=CC=C(P(O)(O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gasparini F, et al. (R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo. J Pharmacol Exp Ther. 1999 Jun;289(3):1678-87. [Content Brief]
[2]. Zhao L, et al. Activation of group III metabotropic glutamate receptor reduces intracellular calcium in beta-amyloid peptide [31-35]-treated cortical neurons. Neurotox Res. 2009 Aug;16(2):174-83. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(RS)-PPG (Standard) Related Classifications
HY-107514R Related Classifications
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