Epoetin alfa
Based on 1 Customer Validation
Epoetin alfa (Epogen) is a recombinant human erythropoietin whose amino acid sequence and biological activity are identical to those of endogenous erythropoietin (EPO). Epoetin alfa is a direct agonist of the EPO receptor (EPOR) on the surface of erythroid progenitor cells, and promotes the production and maturation of red blood cells. Epoetin alfa can be used for research on myelodysplastic syndrome-related anemia and hematological malignancies.
For research use only. We do not sell to patients.
- CAS No.: 113427-24-0
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 113427-24-0
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Epoetin alfa]
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Synonyms
Epogen
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Shipping
Room temperature in continental US; may vary elsewhere.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1].
Gascón P, et al. Epoetin alfa for the treatment of myelodysplastic syndrome-related anemia: A review of clinical data, clinical guidelines, and treatment protocols. Leuk Res. 2019 Jun;81:35-42.
[Content Brief]
[2].
Straus DJ. Epoetin alfa therapy for patients with hematologic malignancies and mild anemia. Clin Lymphoma. 2003 Aug;4 Suppl 1:S13-7.
[Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Epoetin alfa
- 113427-24-0
- Epogen
- Transmembrane Glycoprotein
- Erythropoietin Receptor (EpoR)
- Erythropoietin Receptor
- EpoR
- hematologic malignancies
- chemotherapy
- cancer-related anemia
- erythropoiesis-stimulating agent
- recombinant human erythropoietin
- hemoglobin
- anemic patients
- myelodysplastic syndrome-related anemia
- Inhibitor
- inhibitor
- inhibit