Epoetin alfa
Epoetin alfa (Epogen) is a recombinant human erythropoietin whose amino acid sequence and biological activity are identical to those of endogenous erythropoietin (EPO). Epoetin alfa is a direct agonist of the EPO receptor (EPOR) on the surface of erythroid progenitor cells, and promotes the production and maturation of red blood cells. Epoetin alfa can be used for research on myelodysplastic syndrome-related anemia and hematological malignancies.
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- CAS No.: 113427-24-0
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Stockage:
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Epoetin alfa is produced via recombinant DNA technology in mammalian cells (CHO cells). By binding to EPOR and activating downstream signaling pathways, it stimulates the bone marrow to produce red blood cells[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Product Image
Chemical Information
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CAS No. 113427-24-0
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SMILES
[Epoetin alfa]
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Synonyms
Epogen
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1].
Gascón P, et al. Epoetin alfa for the treatment of myelodysplastic syndrome-related anemia: A review of clinical data, clinical guidelines, and treatment protocols. Leuk Res. 2019 Jun;81:35-42.
[Content Brief]
[2].
Straus DJ. Epoetin alfa therapy for patients with hematologic malignancies and mild anemia. Clin Lymphoma. 2003 Aug;4 Suppl 1:S13-7.
[Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Epoetin alfa Related Classifications
HY-108864 Related Classifications
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