113427-24-0
Chemical Structure
Epoetin alfa
Synonym(s): Epogen
- CAS No.: 113427-24-0
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Epoetin alfa]
Biological Activity: Epoetin alfa (Epogen) is a recombinant human erythropoietin whose amino acid sequence and biological activity are identical to those of endogenous erythropoietin (EPO). Epoetin alfa is a direct agonist of the EPO receptor (EPOR) on the surface of erythroid progenitor cells, and promotes the production and maturation of red blood cells. Epoetin alfa can be used for research on myelodysplastic syndrome-related anemia and hematological malignancies[1][2].
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Epoetin alfa | Epoetin alfa (Epogen) is a recombinant human erythropoietin whose amino acid sequence and biological activity are identical to those of endogenous erythropoietin (EPO). Epoetin alfa is a direct agonist of the EPO receptor (EPOR) on the surface of erythroid progenitor cells, and promotes the production and maturation of red blood cells. Epoetin alfa can be used for research on myelodysplastic syndrome-related anemia and hematological malignancies. | |||||||||||||||||||||
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[1]. Gascón P, et al. Epoetin alfa for the treatment of myelodysplastic syndrome-related anemia: A review of clinical data, clinical guidelines, and treatment protocols. Leuk Res. 2019 Jun;81:35-42.
[Content Brief] -
[2]. Straus DJ. Epoetin alfa therapy for patients with hematologic malignancies and mild anemia. Clin Lymphoma. 2003 Aug;4 Suppl 1:S13-7.
[Content Brief]
Keywords
