Malformin A1
Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9.
For research use only. We do not sell to patients.
- CAS No.: 3022-92-2
- Formula: C23H39N5O5S2
- Molecular Weight:529.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | IC50 |
0.76 μM
Compound: 1; synthetic
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27680590] |
| U-937 | IC50 |
0.8 μM
Compound: 1; natural
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
[PMID: 27680590] |
Chemical Information
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CAS No. 3022-92-2
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Molecular Weight 529.72
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Formula C23H39N5O5S2
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Sequence Shortening
CCVLI (Disulfide bridge:Cys1-Cys2)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)