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Cat. No.: HY-125163

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MM 47755

(Synonyms: 8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin)

MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces.

For research use only. We do not sell to patients.

CAS No.: 117620-87-8
Formula: C₂₀H₁₆O₅
Molecular Weight:336.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

MM 47755 Chemical Structure

CAS No.: 117620-87-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces^[1].

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>100 μM Compound: 4	Cytotoxicity against human HepG2 cells after 2 days by CellTiter-Glo assay Cytotoxicity against human HepG2 cells after 2 days by CellTiter-Glo assay	[PMID: 23025282]
HepG2	IC₅₀	18.5 μM Compound: 4	Antiplasmodial activity against luciferase-expressing sporozoite of Plasmodium berghei ANKA infected in human HepG2 cells assessed as reduction of parasite load after 2 days Antiplasmodial activity against luciferase-expressing sporozoite of Plasmodium berghei ANKA infected in human HepG2 cells assessed as reduction of parasite load after 2 days	[PMID: 23025282]
M14	IC₅₀	9.7 μM Compound: 16	Cytotoxicity against human M14 cells after 72 hrs by MTS assay Cytotoxicity against human M14 cells after 72 hrs by MTS assay	[PMID: 26335269]
MDA-MB-468	IC₅₀	27 μM Compound: 16	Cytotoxicity against human MDA-MB-468 cells after 72 hrs by MTS assay Cytotoxicity against human MDA-MB-468 cells after 72 hrs by MTS assay	[PMID: 26335269]
NCI-H226	IC₅₀	4.6 μM Compound: 16	Cytotoxicity against human NCI-H226 cells after 72 hrs by MTS assay Cytotoxicity against human NCI-H226 cells after 72 hrs by MTS assay	[PMID: 26335269]
SF-295	IC₅₀	17 μM Compound: 16	Cytotoxicity against human SF295 cells after 72 hrs by MTS assay Cytotoxicity against human SF295 cells after 72 hrs by MTS assay	[PMID: 26335269]
SF-539	IC₅₀	10 μM Compound: 16	Cytotoxicity against human SF539 cells after 72 hrs by MTS assay Cytotoxicity against human SF539 cells after 72 hrs by MTS assay	[PMID: 26335269]

In Vitro

MM 47755 has inhibitory activity against Staphylococcus aureus Smith, S. aureus MS9610 (multi-resistant), Micrococcus luteus PCI 1001, Bacillus subtilis NRRLB-558 with MIC values of 12. 5, 12. 5, 25, 12. 5 μg/mL respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 117620-87-8
Molecular Weight 336.34
Formula C₂₀H₁₆O₅
SMILES

O=C1C[C@](C)(O)CC(C1=C2C3=O)=CC=C2C(C4=C3C=CC=C4OC)=O
Synonyms

8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shigihara Y, et al. 6-Deoxy-8-O-methylrabelomycin and 8-O-methylrabelomycin from a Streptomyces species. J Antibiot (Tokyo). 1988 Sep;41(9):1260-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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MM 47755

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MM 47755 Related Classifications

HY-125163 Related Classifications