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Cat. No.: HY-119512

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Ethoxomane

(Synonyms: Ethomoxane)

Ethoxomane (Ethomoxane) is an α-adrenergic receptor blocker. Ethoxomane elevates the hissing threshold induced by perifornical hypothalamic stimulation in cats. Ethoxomane exhibits antihypertensive effects. Ethoxomane can be used in the research of cardiovascular and cerebrovascular diseases.

For research use only. We do not sell to patients.

CAS No.: 3570-46-5
Formula: C₁₅H₂₃NO₃
Molecular Weight:265.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ethoxomane Chemical Structure

CAS No.: 3570-46-5

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

All Adrenergic Receptor Isoforms :

In Vivo

Ethomoxane (2.5 mg/kg; i.p.; single injection) elevates the hypothalamic-induced hissing threshold in adult mongrel cats, with a peak mean threshold increase of approximately 60%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mongrel cats (adult; 1 male, 3 female; hypothalamic electrode implantation)^[1]
Dosage:

2.5 mg/kg (calculated as free base)
Administration:

i.p.; single injection
Result:

Elevated the hypothalamic-induced hissing threshold in all four cats, with a mean percent increase peaking at approximately 60% around 1 hour post-administration, then declining toward baseline by 2 hours post-administration.
Showed no marked changes in general animal behavior.

Chemical Information

CAS No. 3570-46-5
Molecular Weight 265.35
Formula C₁₅H₂₃NO₃
SMILES

CCOC1=C(OC(CNCCCC)CO2)C2=CC=C1
Synonyms

Ethomoxane
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Funderburk WH, et al. Effects of psychotherapeutic drugs on hypothalamic- induced hissing in cats. Neuropharmacology. 1970 Jan;9(1):1-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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