2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Ethoxomane

Ethoxomane (Ethomoxane) is an α-adrenergic receptor blocker. Ethoxomane elevates the hissing threshold induced by perifornical hypothalamic stimulation in cats. Ethoxomane exhibits antihypertensive effects. Ethoxomane can be used in the research of cardiovascular and cerebrovascular diseases.

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Ethoxomane

Ethoxomane Chemical Structure

CAS No. : 3570-46-5

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Ethoxomane Related Antibodies

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Description

Ethoxomane (Ethomoxane) is an α-adrenergic receptor blocker. Ethoxomane elevates the hissing threshold induced by perifornical hypothalamic stimulation in cats. Ethoxomane exhibits antihypertensive effects. Ethoxomane can be used in the research of cardiovascular and cerebrovascular diseases[1].

In Vivo

Ethomoxane (2.5 mg/kg; i.p.; single injection) elevates the hypothalamic-induced hissing threshold in adult mongrel cats, with a peak mean threshold increase of approximately 60%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mongrel cats (adult; 1 male, 3 female; hypothalamic electrode implantation)[1]
Dosage: 2.5 mg/kg (calculated as free base)
Administration: i.p.; single injection
Result: Elevated the hypothalamic-induced hissing threshold in all four cats, with a mean percent increase peaking at approximately 60% around 1 hour post-administration, then declining toward baseline by 2 hours post-administration.
Showed no marked changes in general animal behavior.
Molecular Weight

265.35

Formula

C15H23NO3
CAS No.
SMILES

CCOC1=C(OC(CNCCCC)CO2)C2=CC=C1
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Ethoxomane Related Classifications

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Keywords:

Ethoxomane3570-46-5EthomoxaneAdrenergic ReceptorBeta Receptorα-adrenergic receptor blockercardiovascular and cerebrovascular diseasesInhibitorinhibitorinhibit

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