2. Protein Tyrosine Kinase/RTK
  3. FAK
  4. FAK-IN-3

FAK-IN-3 (Compound 36) is a potent inhibitor of focal adhesion kinase (FAK). FAK-IN-3 not only decreases migration and invasion of PA-1 cells, but also reduces expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis, and no obvious adverse effects. FAK-IN-3 has the potential for the research of ovarian cancer.

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FAK-IN-3

FAK-IN-3 Estructura química

No. CAS : 2882094-29-1

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FAK-IN-3 Related Antibodies

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Descripciòn

FAK-IN-3 (Compound 36) is a potent inhibitor of focal adhesion kinase (FAK). FAK-IN-3 not only decreases migration and invasion of PA-1 cells, but also reduces expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis, and no obvious adverse effects. FAK-IN-3 has the potential for the research of ovarian cancer[1].

Peso molecular

512.56

Fòrmula

C28H28N6O4
No. CAS
SMILES

COC1=CC(C(NC2CCNCC2)=O)=CC=C1NC3=NC4=C(C(OC5=CC=CC6=C5C(CC6)=O)=N3)C=CN4
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Room temperature in continental US; may vary elsewhere.
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FAK-IN-3 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAK-IN-32882094-29-1FAKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinasefocal adhesion kinasemigrationinvasionMMP-2MMP-9tumor growthmetastasisadverse effectsovarian cancerInhibitorinhibitorinhibit

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Nombre del producto:
FAK-IN-3
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HY-143407
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