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Cat. No.: HY-118587

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CH-102

Name: CH-102
Brand: MedChemExpress
SKU: HY-118587
Availability: PreOrder

(Synonyms: HE 165)

CH-102 (HE 165) is an isoquinoline derivative. CH-102 exhibits significant anti-platelet aggregation and antithrombotic activities. CH-102 can be used in the study of angina pectoris.

For research use only. We do not sell to patients.

CAS No.: 55393-37-8
Formula: C₁₄H₁₃N₃O₂S
Molecular Weight:287.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CH-102 Chemical Structure

CAS No.: 55393-37-8

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

CH-102 (HE 165) is an isoquinoline derivative. CH-102 exhibits significant anti-platelet aggregation and antithrombotic activities. CH-102 can be used in the study of angina pectoris^[1]^[2].

In Vitro

CH-102 (2 g; 5 h) shows stability in acidic and neutral aqueous media, but hydrolyzes in alkaline media to form an acid amide derivative (Rf 0.74, m/Z 305) and a carboxylic acid derivative (Rf 0.20, m/Z 262)^[1].
CH-102 (200 μg; 30-minute pre-saturation; 90-minute development time) is effectively separated from its alkaline hydrolysis degradation products (Rf 0.74 and Rf 0.20) using a chloroform-methanol-25% ammonium hydroxide (70:20:2.5, v/v/v) TLC system for stability analysis, with CH-102 having an Rf of 0.92^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 55393-37-8
Molecular Weight 287.34
Formula C₁₄H₁₃N₃O₂S
SMILES

N#CC(SC1=N)=C2N1CCC3=C2C=C(OC)C(OC)=C3
Synonyms

HE 165
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Bernus I, et al. Analytical studies on the hydrolysis of Chinoin-102 and Chinoin-127, candidate compounds for stability studies. Journal of pharmaceutical and biomedical analysis. 1985;3(5):405-15.

[2]. Hou Y, et al. A review of natural compounds to regulate platelet aggregation: molecular mechanism and research advance. Frontiers in pharmacology. 2025;16:1537776.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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