MK-3903 (Standard)
MK-3903 (Standard) is the analytical standard of MK-3903 (HY-107988). This product is intended for research and analytical applications. MK-3903 is a potent and selective AMP-activated protein Kinase (AMPK) activator with an EC50 of 8 nM.
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- No. CAS: 1219737-12-8
- Fòrmula: C27H19ClN2O3
- Peso molecular:454.90
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
EC50: 8 nM (AMPK)[1]
Chemical Information
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No. CAS 1219737-12-8
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Peso molecular 454.90
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Fòrmula C27H19ClN2O3
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SMILES
ClC1=CC2=C(NC(OC3=CC=C(C)C(C(O)=O)=C3)=N2)C=C1C(C=C4)=CC=C4C5=CC=CC=C5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Lan P, Romero FA, et al. Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase. J Med Chem. 2017 Nov 9;60(21):9040-9052. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)