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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
102 Results for "
nerve-growth-factor-
" in MedChemExpress (MCE) Product Catalog:
Products (102)
102 Results for "nerve-growth-factor-" in MCE Product Catalog:
11
11 Publications Verification
Referencia número: HY-18314
No. CAS: 504433-23-2
Target:
Áreas de investigación:
GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth .
7
7 Cited Publications
Target:
Áreas de investigación:
LM11A-31 dihydrochloride, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .
7
7 Cited Publications
Target:
Áreas de investigación:
LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .
5
4
4 Cited Publications
Target:
Áreas de investigación:
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75 NTR selectively over TRKA . Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM .
4
4 Cited Publications
Referencia número: HY-P702778
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Beta-nerve growth factor; Ngf; Beta-NGF; Ngfb; beta nerve growth factor
2
2 Cited Publications
Synonyms: Ostreasterol
2
Target:
Áreas de investigación:
Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.
2
2 Cited Publications
Target:
Áreas de investigación:
PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75 NTR. PD 90780 inhibits NGF-p75 NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12 nnr5 cells, respectively .
2
2
1
1 Cited Publications
Referencia número: HY-A0015
No. CAS: 190786-44-8
Target:
Áreas de investigación:
Neurological Disease Metabolic Disease Inflammation/Immunology
Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .
1
1 Cited Publications
Target:
Áreas de investigación:
DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.
1
1 Cited Publications
Referencia número: HY-I0021
No. CAS: 125602-71-3
Target:
Áreas de investigación:
Bepotastine is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .
1
1 Cited Publications
Referencia número: HY-P70310
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuEarly growth response protein 1/EGR1, His; EGR-1; Early growth response protein 1; Zif268; zinc finger protein 225; NGFI-A ; nerve growth factor-induced protein A;
Referencia número: HY-P99297
No. CAS: 2171034-69-6
Synonyms: ZTS-00508841
Target:
Áreas de investigación:
Referencia número: HY-P99677
No. CAS: 2447755-72-6
Synonyms: ZTS-00075623
Target:
Áreas de investigación:
Referencia número: HY-NP143
No. CAS: 93928-24-6
Referencia número: HY-P99627
No. CAS: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110
Target:
Áreas de investigación:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
