1708936-80-4
1708936-80-4
Chemical Structure
Frunevetmab
Synonym(s): NV-02; PG110; ABT-110
- CAS No.: 1708936-80-4
- Formula:N/A
- Molecular Weight:(148 kDa)
IUPAC Name: N-(4-((2S,3R)-3-((tert-butyldiphenylsilyl)oxy)-1-phenylpyrrolidin-2-yl)thiazol-2-yl)-1-(pyridin-4-ylmethyl)-1H-pyrrole-2-carboxamide
SMILES: [Frunevetmab]
Biological Activity: Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Frunevetmab | ≥95.0% | Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats. | ||||||||||||||||||||
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References
- [1]. Margaret E Gruen, et al. Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats. J Vet Intern Med. 2021 Nov;35(6):2752-2762. [Content Brief]
- [2]. D P Gearing, et al. In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti-Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats. J Vet Intern Med. 2016 Jul;30(4):1129-37. [Content Brief]
Keywords
