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Referencia número: HY-174153

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PSB-22219

PSB-22219 is a highly selective non-nucleotidic ligand acting on P2Y₁₂ receptors (K_D=4.57 nM). PSB-22219 is promising for research of P2Y₁₂ receptor-associated neuroinflammation.

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No. CAS: 1404529-43-6
Fòrmula: C₂₆H₂₆N₄O₄
Peso molecular:458.51

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

PSB-22219 Chemical Structure

No. CAS: 1404529-43-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

PSB-22219 is a highly selective non-nucleotidic ligand acting on P2Y₁₂ receptors (K_D=4.57 nM). PSB-22219 is promising for research of P2Y₁₂ receptor-associated neuroinflammation^[1].

Ver todos los productos específicos de isoformas P2Y Receptor :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	0.9 nM Compound: 50a	Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysis Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysis	[PMID: 25075638]

Chemical Information

No. CAS 1404529-43-6
Peso molecular 458.51
Fòrmula C₂₆H₂₆N₄O₄
SMILES

CC1=CC=C2C(C(C(NC3=CC=C(N4N=CC(C(CCC)=O)=C4C)C=C3)=O)=CN2CC(O)=O)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Al-Hroub H, et al. Selective, Non-nucleotidic Radiotracer for P2Y12 Receptors: Design, Synthesis, Characterization, and Imaging of Brain Slices. J Med Chem. 2025 Jun 12;68(11):11279-11298. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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