MGMT - O-6-methylguanine-DNA methyltransferase Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100155050

About MGMT

Primary_assembly 14: 138,499,309-138,771,540 forward strand.Sscrofa11.1:CM000825.5

This gene has 3 transcripts (splice variants) and 189 orthologues. Ubiquitous expression in liver (RPKM 51.), kidney (RPKM 34.1) and 8 other tissues.

MGMT Products (4)

mRNA Protein Name
XM_021073764.1 XP_020929423.1 methylated-DNA--protein-cysteine methyltransferase isoform X4
XM_001928553.5 XP_001928588.2 methylated-DNA--protein-cysteine methyltransferase isoform X3
XM_005671577.3 XP_005671634.1 methylated-DNA--protein-cysteine methyltransferase isoform X2
XM_005671579.3 XP_005671636.2 methylated-DNA--protein-cysteine methyltransferase isoform X1

MGMT Protein Structure

AdaB

AdaB: COG0350 (62 - 227)

  • 0
  • 100
  • 200
  • 262 a.a.
Protein Preferred Names Protein Names

methylated-DNA--protein-cysteine methyltransferase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13668 Lomeguatrib Inhibitor 99.77% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13057 O6BTG-octylglucoside Inhibitor 95.0% Unkown
HY-175299 Hedgehog IN-11 Inhibitor / Unkown
HY-186228 Anticancer agent 333 / Unkown
HY-180540 MGMT-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MGMT NCBI NCBI:4255