MGMT-IN-1
MGMT-IN-1 (Compound 2) is a light-activated MGMT inhibitor. MGMT-IN-1 can effectively enhance the cytotoxicity of Temozolomide (TMZ) (HY-17364) only under light conditions, significantly increasing the DNA damage caused by TMZ. MGMT-IN-1 can be used for the study of chordoma.
For research use only. We do not sell to patients.
- Formula: C19H17BrN6O5S
- Molecular Weight:521.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA Methyltransferase Isoforms
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Biological Activity
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MGMT |
Chemical Information
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Molecular Weight 521.34
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Formula C19H17BrN6O5S
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SMILES
NC1=NC2=C(C(OCC3=CC(Br)=CS3)=N1)N(C=N2)CC4=CC(OC)=C(C=C4[N+]([O-])=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)