Adra1d - adrenergic receptor, alpha 1d Gene

Also Known as Spr8; Adra1; Gpcr8; [a]1d; Adra-1; Adra1a; alpha1D-AR

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11550

Summary

Enables alpha1-adrenergic receptor activity. Involved in multicellular organism aging; neuron-glial cell signaling; and regulation of blood pressure. Acts upstream of or within negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure and norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure. Predicted to be located in cytosol. Predicted to be integral component of plasma membrane. Is expressed in brain; diencephalon; and forebrain. Orthologous to human ADRA1D (adrenoceptor alpha 1D). [provided by Alliance of Genome Resources, Apr 2022]

Adra1d Products (1)

mRNA Protein Name
NM_013460.5 NP_038488.4 alpha-1D adrenergic receptor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables alpha1-adrenergic receptor activity IDA
IDA: Inferred from direct assay
12595294 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
12595294 MGI
involved in neuron-glial cell signaling IGI
IGI: Inferred from genetic interaction
10493741 MGI
acts upstream of or within norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
12595294 MGI
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
26531127 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1D adrenergic receptor

  • alpha-1A adrenergic receptor

  • alpha-1D adrenoceptor

  • alpha-1D adrenoreceptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135270 ADRA1D receptor antagonist 1 Antagonist 98.03% Unkown
HY-148252 ADRA1D receptor antagonist 1 free base Antagonist / Unkown
HY-RS00410 ADRA1D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adra1d NCBI NCBI:146