Nudt1 - nudix hydrolase 1 Gene

Also Known as Mth1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117260

Summary

Predicted to enable hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides and snoRNA binding activity. Involved in aging; male gonad development; and response to cadmium ion. Located in several cellular components, including acrosomal vesicle; extracellular space; and nuclear membrane. Biomarker of Hypertension. Orthologous to human NUDT1 (nudix hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nudt1 Products (1)

mRNA Protein Name
NM_057120.2 NP_476461.1 oxidized purine nucleoside triphosphate hydrolase

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
10710271 RGD
involved in response to cadmium ion IEP
IEP: Inferred from expression pattern
11817101 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
11817101 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
17280880 RGD
located in nuclear membrane IDA
IDA: Inferred from direct assay
11817101 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxidized purine nucleoside triphosphate hydrolase

7,8-dihydro-8-oxoguanine triphosphatase

  • 2-hydroxy-dATP diphosphatase

  • 8-oxo-dGTPase

  • methylated purine nucleoside triphosphate hydrolase

  • mutT human homolog (8-oxo-dGTPase)

  • nucleoside diphosphate-linked moiety X motif 1

  • nudix (nucleoside diphosphate linked moiety X)-type motif 1

  • nudix motif

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-112081 BAY-707 Inhibitor 99.64% Unkown
HY-158062 LC-1-40 99.65% Unkown
HY-187054 NUDT1 ligand-1 Ligand / Unkown
HY-RS09661 NUDT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18535 Nudt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25017 Nudt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nudt1 NCBI NCBI:4521