Hrk - harakiri, BCL2 interacting protein Gene

Also Known as Dp5; Bid3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117271

Summary

Involved in apoptotic process; cellular response to potassium ion starvation; and positive regulation of neuron apoptotic process. Predicted to be integral component of membrane. Predicted to be active in mitochondrion. Orthologous to human HRK (harakiri, BCL2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Hrk Products (1)

mRNA Protein Name
NM_057130.5 NP_476471.1 activator of apoptosis harakiri

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10075695 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to potassium ion starvation IMP
IMP: Inferred from mutant phenotype
17428807 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
17428807 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

activator of apoptosis harakiri

  • BH3 interacting (with BCL2 family) domain, apoptosis agonist

  • BH3 interacting domain 3

  • BH3-interacting domain-containing protein 3

  • harakiri, BCL2 interacting protein (contains only BH3 domain)

  • neuronal death protein DP5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P5342 Hrk BH3 99.74% Unkown
HY-180948 PZ-11 Inducer / Unkown
HY-RS06371 HRK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21284 Hrk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27803 Hrk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hrk NCBI NCBI:8739