Cd24a - CD24a antigen Gene

Also Known as HSA; Cd24; Ly-52; nectadrin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12484

Summary

Enables HSP70 protein binding activity; HSP90 protein binding activity; and carbohydrate binding activity. Involved in several processes, including Chemokine Receptor transport out of membrane raft; negative regulation of cytokine production; and regulation of inflammatory response to wounding. Acts upstream of or within several processes, including positive regulation of immune response; regulation of cell-cell adhesion; and regulation of lymphocyte activation. Located in cell projection membrane; external side of plasma membrane; and membrane raft. Is anchored component of external side of plasma membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; hemolymphoid system; hindlimb; and retina. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CD24 (CD24 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd24a Products (1)

mRNA Protein Name
NM_009846.2 NP_033976.1 signal transducer CD24 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables Hsp70 protein binding IDA
IDA: Inferred from direct assay
19264983 MGI
enables Hsp90 protein binding IDA
IDA: Inferred from direct assay
19264983 MGI
enables carbohydrate binding IDA
IDA: Inferred from direct assay
15633604 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
7524641 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of B cell apoptotic process IDA
IDA: Inferred from direct assay
8920854 MGI
acts upstream of B cell proliferation IDA
IDA: Inferred from direct assay
8920854 MGI
acts upstream of CD4-positive, alpha-beta T cell proliferation IDA
IDA: Inferred from direct assay
8125140 MGI
acts upstream of CD4-positive, alpha-beta T cell proliferation IMP
IMP: Inferred from mutant phenotype
15314074 MGI
acts upstream of T cell homeostatic proliferation IMP
IMP: Inferred from mutant phenotype
15477346 MGI
acts upstream of or within apoptotic mitochondrial changes IDA
IDA: Inferred from direct assay
14707049 MGI
acts upstream of or within apoptotic nuclear changes IDA
IDA: Inferred from direct assay
14707049 MGI
acts upstream of or within apoptotic signaling pathway IDA
IDA: Inferred from direct assay
8920854 MGI
acts upstream of calcium-mediated signaling IDA
IDA: Inferred from direct assay
7613634 MGI
involved in cell migration IMP
IMP: Inferred from mutant phenotype
16390867 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: Inferred from direct assay
7613634 MGI
involved in chemokine receptor transport out of membrane raft IMP
IMP: Inferred from mutant phenotype
16390867 MGI
involved in cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
16390867 MGI
acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: Inferred from direct assay
8145052 MGI
acts upstream of or within homotypic cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
7613634 MGI
acts upstream of integrin activation IDA
IDA: Inferred from direct assay
10601245 MGI
acts upstream of integrin activation IMP
IMP: Inferred from mutant phenotype
10601245 MGI
acts upstream of or within leukocyte cell-cell adhesion IDA
IDA: Inferred from direct assay
7534304 MGI
acts upstream of or within leukocyte migration involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
15314074 MGI
acts upstream of or within negative regulation of B cell proliferation IDA
IDA: Inferred from direct assay
8920854 MGI
acts upstream of or within negative regulation of T cell homeostatic proliferation IMP
IMP: Inferred from mutant phenotype
16769998 MGI
acts upstream of or within negative regulation of erythrocyte aggregation IMP
IMP: Inferred from mutant phenotype
9028339 MGI
acts upstream of or within negative regulation of erythrocyte clearance IMP
IMP: Inferred from mutant phenotype
9028339 MGI
involved in negative regulation of inflammatory response to wounding IPI
IPI: Inferred from physical interaction
19264983 MGI
involved in negative regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
19264983 MGI
involved in negative regulation of monocyte chemotactic protein-1 production IMP
IMP: Inferred from mutant phenotype
19264983 MGI
acts upstream of or within negative regulation of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
11978835 MGI
acts upstream of or within negative regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
15737737 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
15737737 MGI
involved in negative regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
19264983 MGI
acts upstream of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
11978835 MGI
acts upstream of or within neuromuscular synaptic transmission IGI
IGI: Inferred from genetic interaction
16606832 MGI
acts upstream of or within neuromuscular synaptic transmission IMP
IMP: Inferred from mutant phenotype
16606832 MGI
acts upstream of neuron projection development IDA
IDA: Inferred from direct assay
19458237 MGI
acts upstream of or within neuron projection development IDA
IDA: Inferred from direct assay
11283023 MGI
acts upstream of neuron projection development IGI
IGI: Inferred from genetic interaction
19458237 MGI
acts upstream of or within neuron projection development IMP
IMP: Inferred from mutant phenotype
11283023 MGI
acts upstream of peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
9177270 MGI
acts upstream of or within positive regulation of B cell apoptotic process IDA
IDA: Inferred from direct assay
8920854 MGI
acts upstream of or within positive regulation of CD4-positive, alpha-beta T cell proliferation IDA
IDA: Inferred from direct assay
8125140 MGI
acts upstream of or within positive regulation of CD4-positive, alpha-beta T cell proliferation IMP
IMP: Inferred from mutant phenotype
15314074 MGI
acts upstream of or within positive regulation of T cell homeostatic proliferation IMP
IMP: Inferred from mutant phenotype
15477346 MGI
acts upstream of or within positive regulation of T cell mediated immune response to tumor cell IDA
IDA: Inferred from direct assay
7774619 MGI
acts upstream of or within positive regulation of alpha-beta T cell proliferation IDA
IDA: Inferred from direct assay
1346270 MGI
acts upstream of or within positive regulation of alpha-beta T cell proliferation IMP
IMP: Inferred from mutant phenotype
1385153 MGI
acts upstream of or within positive regulation of calcium-mediated signaling IDA
IDA: Inferred from direct assay
7613634 MGI
acts upstream of or within positive regulation of cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
10601245 MGI
acts upstream of or within positive regulation of cell adhesion mediated by integrin IMP
IMP: Inferred from mutant phenotype
10601245 MGI
acts upstream of or within positive regulation of cell-cell adhesion IDA
IDA: Inferred from direct assay
7669058 MGI
acts upstream of or within positive regulation of cell-cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
7534304 MGI
acts upstream of or within positive regulation of inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
10791997 MGI
involved in positive regulation of inflammatory response to wounding IMP
IMP: Inferred from mutant phenotype
19264983 MGI
acts upstream of or within positive regulation of integrin activation IDA
IDA: Inferred from direct assay
7534304 MGI
acts upstream of or within positive regulation of integrin activation IMP
IMP: Inferred from mutant phenotype
10601245 MGI
acts upstream of or within positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
19458237 MGI
acts upstream of or within positive regulation of neuron projection development IGI
IGI: Inferred from genetic interaction
19458237 MGI
acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
9177270 MGI
acts upstream of or within pre-B cell differentiation IMP
IMP: Inferred from mutant phenotype
7795661 MGI
acts upstream of or within regulation of B cell differentiation IMP
IMP: Inferred from mutant phenotype
7795661 MGI
acts upstream of or within regulation of cell-cell adhesion IDA
IDA: Inferred from direct assay
8117278 MGI
acts upstream of or within regulation of cell-cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
8145052 MGI
involved in regulation of cytokine-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
16390867 MGI
involved in response to molecule of bacterial origin IDA
IDA: Inferred from direct assay
15493995 MGI
acts upstream of or within synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
16606832 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
9324354 MGI
located in ciliary membrane IDA
IDA: Inferred from direct assay
11978835 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
1346270 MGI
located in membrane IDA
IDA: Inferred from direct assay
11283023 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
15493995 MGI
located in microvillus membrane IDA
IDA: Inferred from direct assay
11978835 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
35087169 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11978835 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

signal transducer CD24

  • M1/69-J11D heat stable antigen

  • R13-Ag

  • X62 heat stable antigen

  • cluster of differentiation 24

  • heat stable antigen

  • lymphocyte antigen 52

Recombinant Cd24a Proteins

Cat. No. Product Name Accession Purity
HY-P72747 CD24 Protein, Mouse (HEK293, hFc) P24807 (N27-G53) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78255 CD24 Protein, Mouse (HEK293, mFc) P24807 (N27-G53) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02212 CD24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23018 Cd24 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown