Gss - glutathione synthetase Gene

Also Known as GSH-S; GS-A/GS-B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14854

Summary

Enables glutathione synthase activity. Acts upstream of or within response to cadmium ion. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; glutathione synthetase deficiency; and hemolytic anemia due to glutathione synthetase deficiency. Orthologous to human GSS (glutathione synthetase). [provided by Alliance of Genome Resources, Apr 2022]

Gss Products (2)

mRNA Protein Name
NM_001291111.1 NP_001278040.1 glutathione synthetase isoform b
NM_008180.2 NP_032206.1 glutathione synthetase isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables glutathione synthase activity IDA
IDA: Inferred from direct assay
8660701 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to cadmium ion IDA
IDA: Inferred from direct assay
8660701 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione synthetase

  • GSH synthetase

  • glutathione synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113306 1-Methyladenine 99.99% Unkown
HY-W015600 2-Acetamidophenol 99.73% Unkown
HY-W015600S 2-Acetamidophenol-d3 99.48% Unkown
HY-RS05871 GSS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11188 PRNP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17796 Gss Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24264 Gss Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gss NCBI NCBI:2937