MEI1 - meiotic double-stranded break formation protein 1 Gene

Also Known as HYDM3; SPATA38

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 150365

About MEI1

Cytogenetic location: 22q13.2 Genomic coordinates (GRCh38): 22:41,699,503-41,799,454 (from NCBI)

This gene has 16 transcripts (splice variants), 181 orthologues, 2 paralogues and is associated with 2 phenotypes. Biased expression in testis (RPKM 5.5), spleen (RPKM 2.0) and 13 other tissues.

Summary

Predicted to be involved in meiosis I. Predicted to act upstream of or within gamete generation; meiotic spindle organization; and meiotic telomere clustering. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MEI1 Products (1)

mRNA Protein Name
NM_152513.4 NP_689726.3 meiosis inhibitor protein 1
Protein Preferred Names Protein Names

meiosis inhibitor protein 1

  • meiosis defective 1

Related Diseases

Diseases Alias
Hydatidiform Mole, Recurrent, 3

  • HYDM3
Hydatidiform Mole, Recurrent, 1

  • Hydatidiform Mole

  • Gestational Trophoblastic Disease

  • Complete Hydatidiform Mole

  • Hydm

  • HYDM1

  • Chm

  • Molar Pregnancy

  • Hydatidiform Mole, Complete

  • Hydatid Mole

  • Complete Molar Pregnancy

  • Mole, Hydatidiform, Recurrent, Type 1

  • Gestational Trophoblastic Neoplasms

  • Hydatidiform Mole, Recurrent, 2

  • Classical Hydatidiform Mole
Trophoblastic Neoplasm

  • Trophoblastic Tumor

  • Trophoblastic Neoplasms
Gestational Trophoblastic Neoplasm

  • Hydatidiform Mole

  • Molar Pregnancy

  • Gestational Trophoblastic Neoplasia

  • Gestational Trophoblastic Tumor

  • Gtn

  • Gestational Trophoblastic Disease

  • Gestational Trophoblastic Neoplasms

  • Hydatidiform Mole, Recurrent, 1

  • Hydatidiform Mole Benign

  • Trophoblastic Disease

  • Trophoblastic Disease Nos

  • Trophoblastic Disorder

  • Vesicular Mole Nos

  • Vesicular Mole

  • Hydatidiform Mole Nos
Lumbosacral Lipoma
Spermatogenic Failure 5

  • Male Infertility With Large-Headed, Multiflagellar, Polyploid Spermatozoa

  • Infertility Associated With Multi-Tailed Spermatozoa And Excessive Dna

  • SPGF5

  • Macrocephalic Sperm Head Syndrome

  • Male Infertility Due To Macrozoospermia

  • Infertility Associated With Multitailed Spermatozoa And Excessive Dna

  • Macrozoospermia

  • Male Infertility Due To Large-Headed Multiflagellar Polyploid Spermatozoa

  • Infertility Associated With Multi-Tailed Spermatozoa And Excessive Deoxyribonucleic Acid

  • Large-Headed Multiflagellar Polyploid Spermatozoa

  • Male Infertility With Large-Headed Multiflagellar Polyploid Spermatozoa
Cerebrooculofacioskeletal Syndrome 2

  • COFS2

  • Cerebro-Oculo-Facio-Skeletal Syndrome 2

  • Cofs Syndrome
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15227 EPZ004777 99.74% Unkown
HY-156794 Enzomenib Inhibitor 99.88% Unkown
HY-134258 MEISi-1 Inhibitor 98.16% Unkown
HY-15222 Menin-MLL inhibitor MI-2 99.41% Unkown
HY-15227A EPZ004777 hydrochloride 98.92% Unkown
HY-132870 MEIS-IN-2 Inhibitor 99.33% Unkown
HY-172416 Balomenib Inhibitor 99.81% Unkown
HY-155797 (S)-Bleximenib 96.06% Unkown
HY-RS08325 MEIS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-156794A Enzomenib enantiomer Inhibitor 98.01% Unkown
HY-115619 EPZ004777 formate / Unkown
HY-15222A Menin-MLL inhibitor MI-2 dihydrochloride / Unkown
HY-155526 FY-21 Inhibitor / Unkown
HY-160018 BAY-155 Inhibitor / Unkown
HY-160733 Menin-MLL-IN-32 Inhibitor / Unkown
HY-178172 AF9/ENL-DOT1L PPI-IN-1 Inhibitor / Unkown
HY-RS08319 MEI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-186043 Menin-MLL-IN-35 Inhibitor / Unkown
HY-186044 Menin-MLL-IN-36 Inhibitor / Unkown
HY-RS19217 Meis1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21374 Mei1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25706 Meis1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27893 Mei1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MEI1 MGD MGI:3028590
Bos taurus MEI1 VGNC VGNC:31378
Felis catus MEI1 VGNC VGNC:63446
Canis familiaris MEI1 VGNC VGNC:43149
Macaca mulatta MEI1 VGNC VGNC:95361
Rattus norvegicus MEI1 RGD RGD:1307210
Others MEI1 NCBI