2. Epigenetics Apoptosis
  3. Epigenetic Reader Domain Apoptosis
  4. Menin-MLL inhibitor MI-2 dihydrochloride

Menin-MLL inhibitor MI-2 dihydrochloride is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 dihydrochloride downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 dihydrochloride is proming for rasearch of MLL-rearranged acute leukemias (e.g., AML, ALL).

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Menin-MLL inhibitor MI-2 dihydrochloride

Menin-MLL inhibitor MI-2 dihydrochloride 화학구조

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제품 설명

Menin-MLL inhibitor MI-2 dihydrochloride is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 dihydrochloride downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 dihydrochloride is proming for rasearch of MLL-rearranged acute leukemias (e.g., AML, ALL)[1].

분자량

448.48

화학식

C18H27Cl2N5S2
SMILES

CCCC1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(C)(S4)C.Cl.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Keywords:

Menin-MLL inhibitor MI-2Epigenetic Reader DomainApoptosisMenin-MLLHOXA9MEIS1MLL-rearranged acute leukemiasInhibitorinhibitorinhibit

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상품명:
Menin-MLL inhibitor MI-2 dihydrochloride
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HY-15222A
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