Menin-MLL-IN-32
Menin-MLL-IN-32 (compound 51) is a Menin-MLL interaction inhibitor with an IC50 of 0.042 nM in HTRF assay. Menin-MLL-IN-32 inhibits MEIS1 mRNA expression with an IC50 of 11 nM. Menin-MLL-IN-32 shows anti-proliferative effects, with IC50 values of 8 nM, 24 nM and 1900 nM for MOLM14 cells, OCI-AML3 cells and KO-52 cells, respectively. Menin-MLL-IN-32 can be used for the study of leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2879330-24-0
- Formula: C32H42FN5O2
- Molecular Weight:547.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2879330-24-0
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Molecular Weight 547.71
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Formula C32H42FN5O2
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SMILES
CC(C)N(C)C(C1=C(C=CC(F)=C1)N2C3=CN=CC(C)=C3C(C[C@H]4CN(CC4)CC5CCN(CC5)C(C)=O)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)