2. Epigenetics
  3. Epigenetic Reader Domain
  4. Menin-MLL-IN-32

Menin-MLL-IN-32 (compound 51) is a Menin-MLL interaction inhibitor with an IC50 of 0.042 nM in HTRF assay. Menin-MLL-IN-32 inhibits MEIS1 mRNA expression with an IC50 of 11 nM. Menin-MLL-IN-32 shows anti-proliferative effects, with IC50 values of 8 nM, 24 nM and 1900 nM for MOLM14 cells, OCI-AML3 cells and KO-52 cells, respectively. Menin-MLL-IN-32 can be used for the study of leukemia.

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Menin-MLL-IN-32

Menin-MLL-IN-32 Chemical Structure

CAS No. : 2879330-24-0

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Menin-MLL-IN-32 Related Antibodies

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Description

Menin-MLL-IN-32 (compound 51) is a Menin-MLL interaction inhibitor with an IC50 of 0.042 nM in HTRF assay. Menin-MLL-IN-32 inhibits MEIS1 mRNA expression with an IC50 of 11 nM. Menin-MLL-IN-32 shows anti-proliferative effects, with IC50 values of 8 nM, 24 nM and 1900 nM for MOLM14 cells, OCI-AML3 cells and KO-52 cells, respectively. Menin-MLL-IN-32 can be used for the study of leukemia[1].

Molecular Weight

547.71

Formula

C32H42FN5O2
CAS No.
SMILES

CC(C)N(C)C(C1=C(C=CC(F)=C1)N2C3=CN=CC(C)=C3C(C[C@H]4CN(CC4)CC5CCN(CC5)C(C)=O)=C2)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Menin-MLL-IN-32 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Menin-MLL-IN-322879330-24-0Epigenetic Reader DomainMenin-MLL Interaction InhibitorleukemiaMEIS1 mRNA expressionInhibitorinhibitorinhibit

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