Il3ra - interleukin 3 receptor, alpha chain Gene

Also Known as CD123; SUT-1; CDw123

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16188

Summary

Enables interleukin-3 binding activity and interleukin-3 receptor activity. Acts upstream of or within interleukin-3-mediated signaling pathway; monocyte differentiation; and regulation of cell growth. Located in membrane. Is expressed in several structures, including cardiovascular system mesenchyme; dorsal aorta; early conceptus; genitourinary system; and umbilical or vitelline vessel. Orthologous to human IL3RA (interleukin 3 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il3ra Products (1)

mRNA Protein Name
NM_008369.1 NP_032395.1 interleukin-3 receptor subunit alpha precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within interleukin-3-mediated signaling pathway IDA
IDA: Inferred from direct assay
19109256 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-3 receptor subunit alpha

  • IL-3 receptor alpha chain

  • IL-3 receptor subunit alpha

  • IL-3R subunit alpha

  • IL-3R-alpha

  • IL-3RA

  • Il-3 alpha subunit

  • interleukin-3 receptor class II alpha chain

Recombinant Il3ra Proteins

Cat. No. Product Name Accession Purity
HY-P72542 IL-3R alpha/CD123 Protein, Mouse (HEK293, His) P26952-1 (S17-K331) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75862 IL-3R alpha/CD123 Protein, Mouse (HEK293, Fc) P26952-1 (S17-K331) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991282 KHK2823 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06764 IL3RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174605 Human IL3RA mRNA / Unkown
Bioactive MoleculesInhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991699 Lixarkitug Inhibitor 99% Unkown
HY-P990451 Anti-IL-3Ra/CD123 Antibody (SNG-CD123A) Inhibitor 95.01% Unkown
HY-P992032 TPP-9476 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il3ra NCBI NCBI:3563