2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  3. ADC Antibody Interleukin Related
  4. Lixarkitug

Lixarkitug  (Synonyms: AZD9829 antibody; INT-020)

Cat. No.: HY-P991699 Purity: 99%
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Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML). The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

CAS No. : 3035710-69-8

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Lixarkitug Related Antibodies

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Description

Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML)[1][2]. The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

IL-3

 

In Vitro

Lixarkitug is a monoclonal antibody defined by a 449-amino-acid heavy chain and 219-amino-acid light chain, with a conjugated form (lixarkitug samrotecan) sharing identical chain lengths.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lixarkitug Related Antibodies
Gene ID

3563  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

146.147 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

N/A
Shipping

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG1-kappa
Purity & Documentation
References
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Lixarkitug Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lixarkitug3035710-69-8AZD9829 antibody INT-020INT020INT 020INT-020ADC AntibodyInterleukin RelatedILlixarkitug samrotecanlight chainsamrotecanheavy chainmonoclonal antibodyInhibitorinhibitorinhibit

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