Ldb2 - LIM domain binding 2 Gene

Also Known as Ldb3; CLIM1; CLP-36

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16826

Summary

Enables LIM domain binding activity and enzyme binding activity. Involved in regulation of cell migration and regulation of kinase activity. Acts upstream of or within several processes, including epithelial structure maintenance; hair follicle development; and somatic stem cell population maintenance. Located in cell leading edge. Part of transcription regulator complex. Is expressed in several structures, including brain; branchial arch; eye; genitourinary system; and limb. Orthologous to human LDB2 (LIM domain binding 2). [provided by Alliance of Genome Resources, Apr 2022]

Ldb2 Products (6)

mRNA Protein Name
NM_001077398.2 NP_001070866.1 LIM domain-binding protein 2 isoform 2
NM_001286348.1 NP_001273277.1 LIM domain-binding protein 2 isoform 3
NM_001347349.1 NP_001334278.1 LIM domain-binding protein 2 isoform 4
NM_001359070.1 NP_001345999.1 LIM domain-binding protein 2 isoform 5
NM_001359071.1 NP_001346000.1 LIM domain-binding protein 2 isoform 6
NM_010698.4 NP_034828.3 LIM domain-binding protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
11882901 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9860983 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of cellular component biogenesis IGI
IGI: Inferred from genetic interaction
17991461 MGI
acts upstream of or within epithelial structure maintenance IGI
IGI: Inferred from genetic interaction
17991461 MGI
acts upstream of or within hair follicle development IGI
IGI: Inferred from genetic interaction
17991461 MGI
acts upstream of or within positive regulation of cellular component biogenesis IGI
IGI: Inferred from genetic interaction
17991461 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
9192866 MGI
involved in regulation of cell migration IMP
IMP: Inferred from mutant phenotype
19675209 MGI
involved in regulation of kinase activity IDA
IDA: Inferred from direct assay
19675209 MGI
acts upstream of or within somatic stem cell population maintenance IGI
IGI: Inferred from genetic interaction
17991461 MGI
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
19675209 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
9192866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LIM domain-binding protein 2

  • LIM domain-binding factor CLIM1

  • carboxyl-terminal LIM domain-binding protein 1

Ldb2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ldb2 O55203 Rlim Mus musculus Q9WTV7
Pull Down
17848518
Intra
Ldb2 O55203 Rlim Mus musculus Q9WTV7
Anti Bait CoIP
17848518
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07569 LDB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ldb2 NCBI NCBI:9079