Rlim - ring finger protein, LIM domain interacting Gene

Also Known as Ha1r; Rlim1; Rnf12

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19820

Summary

Enables ubiquitin protein Ligase activity. Involved in protein ubiquitination; random inactivation of X chromosome; and ubiquitin-dependent protein catabolic process. Acts upstream of or within negative regulation of DNA-binding transcription factor activity; negative regulation of transcription by RNA polymerase II; and regulation of dosage compensation by inactivation of X chromosome. Located in nucleus. Is expressed in several structures, including extraembryonic component; limb; liver; male reproductive system; and urinary system. Human ortholog(s) of this gene implicated in Tonne-Kalscheuer syndrome. Orthologous to human RLIM (ring finger protein, LIM domain interacting). [provided by Alliance of Genome Resources, Apr 2022]

Rlim Products (2)

mRNA Protein Name
NM_001358205.1 NP_001345134.1 E3 ubiquitin-protein ligase RLIM
NM_011276.4 NP_035406.3 E3 ubiquitin-protein ligase RLIM
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RLIM

  • Hoxa1 regulated

  • LIM domain-interacting RING finger protein

  • RING finger LIM domain-binding protein

  • RING-type E3 ubiquitin transferase RLIM

  • ring finger protein 12

Rlim Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rlim Q9WTV7 Zfp42 Mus musculus P22227
Pull Down
22596162
Intra
Rlim Q9WTV7 Zfp42 Mus musculus P22227
Anti Tag CoIP
22596162
Intra
Rlim Q9WTV7 Zfp42 Mus musculus P22227
Anti Bait CoIP
22596162
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12008 RLIM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22305 Rlim Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rlim NCBI NCBI:51132