Epha7 - Eph receptor A7 Gene

Also Known as EHK-3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171287

Summary

Enables Ephrin Receptor binding activity and protein tyrosine kinase activity. Involved in phosphorylation and positive regulation of apoptotic process. Located in dendrite; neuronal cell body; and postsynaptic membrane. Is active in several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and hippocampal mossy fiber to CA3 synapse. Is integral component of postsynaptic density membrane. Orthologous to human EphA7 (EPH receptor A7). [provided by Alliance of Genome Resources, Apr 2022]

Epha7 Products (1)

mRNA Protein Name
NM_134331.2 NP_599158.1 ephrin type-A receptor 7 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ephrin receptor binding IDA
IDA: Inferred from direct assay
10366629 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9883737 RGD
enables protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
9883737 RGD
Biological Process GO Annotation Evidence References Source
involved in phosphorylation IDA
IDA: Inferred from direct assay
9883737 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16983667 RGD
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
26780036 RGD
located in dendrite IDA
IDA: Inferred from direct assay
10792438 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26780036 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
26780036 RGD
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
11414792 RGD
located in neuromuscular junction IDA
IDA: Inferred from direct assay
11414792 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10792438 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
26780036 RGD
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
9922461 RGD
is active in postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
11414792 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-A receptor 7

  • EPH homology kinase 3

  • ephrin receptor EphA7

  • tyrosine-protein kinase receptor EHK-3

Recombinant Epha7 Proteins

Cat. No. Product Name Accession Purity
HY-P76319 EphA7 Protein, Rat (HEK293, Fc) P54759-1 (Q28-S539) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P76320 EphA7 Protein, Rat (HEK293, His) P54759-1 (Q28-S539) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04431 EPHA7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17251 Epha7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23705 Epha7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epha7 NCBI NCBI:2045