Foxc2 - forkhead box C2 Gene

Also Known as Fkh14; Fkhl14; Hfhbf3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171356

Summary

Enables DNA binding activity. Predicted to be involved in several processes, including negative regulation of cold-induced thermogenesis; positive regulation of cell migration involved in sprouting angiogenesis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including animal organ development; cell surface receptor signaling pathway; and vasculature development. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in several diseases, including lymphedema; lymphedema-distichiasis syndrome; obesity; ptosis; and type 2 diabetes mellitus. Orthologous to human FOXC2 (forkhead box C2). [provided by Alliance of Genome Resources, Apr 2022]

Foxc2 Products (1)

mRNA Protein Name
NM_001101680.1 NP_001095150.1 forkhead box protein C2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7683413 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein C2

  • BF-3

  • HFH-BF-3

  • brain factor 3

  • forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-149894 MC-1-F2 Inhibitor 99.69% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxc2 NCBI NCBI:2303