2. Gene
  3. Hexim1 - hexamethylene bis-acetamide inducible 1 Gene

Hexim1 - hexamethylene bis-acetamide inducible 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Clp1; HIS1; CLP-1; 7330426E13Rik

Gene ID: 192231 | Gene type: protein coding

About Hexim1

Summary

Predicted to enable several functions, including 7SK snRNA binding activity; P-TEFb complex binding activity; and cyclin-dependent protein serine/threonine kinase inhibitor activity. Acts upstream of or within heart development and negative regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including branchial arch; embryo mesenchyme; heart and pericardium; hindgut dorsal mesentery; and sensory organ. Orthologous to human HEXIM1 (HEXIM P-TEFb complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Hexim1 Products(1)

mRNA Protein Name
NM_138753.2 NP_620092.1 protein HEXIM1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23663783 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
15172687 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12119119 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
12119119 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein HEXIM1

cardiac lineage protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-163282 NB512 Inhibitor / Unkown
HY-RS06145 HEXIM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hexim1 NCBI NCBI:10614