HEXIM1 - HEXIM P-TEFb complex subunit 1 Gene

Homo sapiens

Also known as CLP1; EDG1; HIS1; MAQ1

Gene ID: 10614 | Gene type: protein coding

About HEXIM1

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:45,148,475-45,152,099 (from NCBI)

This gene has 1 transcript (splice variant), 116 orthologues and 1 paralogue.

Summary

Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns. [provided by RefSeq, Jul 2008]

HEXIM1 Products(1)

mRNA	Protein	Name
NM_006460.3	NP_006451.1	protein HEXIM1

HEXIM1 Protein Structure

HEXIM

0
100
200
300
359 a.a.

Protein Preferred Names

Protein Names

protein HEXIM1

HMBA-inducible

Related Diseases

Diseases

Alias

Nut Midline Carcinoma

Nuclear Protein In Testis Midline Carcinoma

Nmc

Immune Deficiency Disease

Immunodeficiency	Primary Immunodeficiency
Primary Immunodeficiency Disease	Immunologic Deficiency Syndromes
Hypoimmunity	Immune Deficiency Disorder
Immunodeficiency Syndrome	Immune Disorder
Primary Immune Deficiency Disorder	Immune System Diseases
Human Immunodeficiency Virus Infection	Hiv - [Human Immunodeficiency Virus Infection]
Hiv Positive Nos	Hiv Disease
Acquired Immune Deficiency Syndrome-Related Complex	Aids-Like Syndrome
Aids-Related Complex Nos	Arc - [Aids-Related Complex]
Immunodeficiency Due To Human Immunodeficiency Virus Infection	Unspecified Human Immunodeficiency Virus Disease
Hiv Disease Nos	Human Immunodeficiency Virus Positive Nos
Hiv Nos	Deficiency Of Complement Initial Pathway
Deficiency Of Complement Terminal Pathway	Cfdd - [Complement Factor D Deficiency]
Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency	Nonfamilial Hypogammaglobulinaemia
Common Variable Immune Deficiency	Nonfamilial Agammaglobulinaemia
Common Variable Agammaglobulinaemia	Agammaglobulinaemia Nos
Agammaglobulinaemia Antibody Deficiency Syndrome	Hypogammaglobulinaemia Antibody Deficiency Syndrome
Acquired Agammaglobulinaemia Nos	Hypogammaglobulinaemia Nos
Hyper Igm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-163282	NB512	Inhibitor	/	Unkown
HY-RS06145	HEXIM1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	HEXIM1	VGNC	VGNC:62803
Macaca mulatta	HEXIM1	VGNC	VGNC:104615
Mus musculus	HEXIM1	MGD	MGI:2385923
Rattus norvegicus	HEXIM1	RGD	RGD:1559851
Bos taurus	HEXIM1	VGNC	VGNC:29826
Canis familiaris	HEXIM1	VGNC	VGNC:41670

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