Stra8 - stimulated by retinoic acid gene 8 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20899

Summary

Involved in several processes, including activation of meiosis; cellular response to retinoic acid; and germ cell development. Located in cytoplasm and nucleus. Is expressed in central nervous system; ganglia; gonad; spleen primordium; and trophoblast giant cell. Orthologous to human STRA8 (stimulated by retinoic acid 8). [provided by Alliance of Genome Resources, Apr 2022]

Stra8 Products (3)

mRNA Protein Name
NM_001410379.1 NP_001397308.1 stimulated by retinoic acid gene 8 protein isoform 2
NM_001410380.1 NP_001397309.1 stimulated by retinoic acid gene 8 protein isoform 3
NM_009292.3 NP_033318.1 stimulated by retinoic acid gene 8 protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22674187 MGI
Biological Process GO Annotation Evidence References Source
involved in activation of meiosis IMP
IMP: Inferred from mutant phenotype
32032549 MGI
involved in cellular response to retinoic acid IMP
IMP: Inferred from mutant phenotype
19301398 MGI
involved in male germ-line stem cell asymmetric division IMP
IMP: Inferred from mutant phenotype
25902548 MGI
involved in meiotic cell cycle IMP
IMP: Inferred from mutant phenotype
32032549 MGI
involved in oogenesis IMP
IMP: Inferred from mutant phenotype
32032549 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19805549 MGI
involved in regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
32032549 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
32032549 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8896602 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
25972016 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19805549 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

stimulated by retinoic acid gene 8 protein

Stra8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Stra8 P70278 Arid4b Mus musculus A2CG63
Y2H
22674187
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W011094 Win 18446 Inhibitor 98.94% Unkown
HY-RS13958 STRA8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stra8 NCBI NCBI:346673