Ucn - urocortin Gene

Also Known as Ucn1; Mpv17

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22226

Summary

This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. Mice lacking the encoded protein exhibit a heightened anxiety-like behaviors and a significantly reduced acoustic startle response. [provided by RefSeq, Sep 2016]

Ucn Products (2)

mRNA Protein Name
NM_001346010.1 NP_001332939.1 urocortin preproprotein
NM_021290.2 NP_067265.1 urocortin preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
12091910 MGI
NOT involved in prepulse inhibition IMP
IMP: Inferred from mutant phenotype
12192058 MGI
involved in response to auditory stimulus IMP
IMP: Inferred from mutant phenotype
12091910 MGI
NOT involved in response to immobilization stress IMP
IMP: Inferred from mutant phenotype
12091910 MGI
NOT involved in response to starvation IMP
IMP: Inferred from mutant phenotype
12091910 MGI
involved in startle response IMP
IMP: Inferred from mutant phenotype
12192058 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urocortin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13661 7-Hydroxystaurosporine 97.8% Phase 2

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1858A Urocortin III, mouse TFA Activator 98.06% Unkown
HY-105416 Calphostin C Inhibitor 99.9% Unkown
HY-108262 UCN-02 Inhibitor ≥98.0% Unkown
HY-P1858 Urocortin III, mouse Activator 98.29% Unkown
HY-RS15407 UCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15408 UCN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15409 UCN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17732 Ucn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21451 Ucn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24197 Ucn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27969 Ucn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucn NCBI NCBI:7349