Arfgap1 - ADP-ribosylation factor GTPase activating protein 1 Gene

Also Known as Arf1gap

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228998

Summary

Predicted to enable GTPase activator activity. Acts upstream of or within regulation of endocytosis. Located in postsynaptic density. Is expressed in axial skeleton; craniocervical region bone; inner ear; and lower jaw mesenchyme. Orthologous to human ARFGAP1 (ADP ribosylation factor GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Arfgap1 Products (10)

mRNA Protein Name
NM_001177706.2 NP_001171177.1 ADP-ribosylation factor GTPase-activating protein 1 isoform b
NM_001177707.1 NP_001171178.1 ADP-ribosylation factor GTPase-activating protein 1 isoform c
NM_001177708.1 NP_001171179.1 ADP-ribosylation factor GTPase-activating protein 1 isoform c
NM_001177709.1 NP_001171180.1 ADP-ribosylation factor GTPase-activating protein 1 isoform b
NM_001177710.1 NP_001171181.1 ADP-ribosylation factor GTPase-activating protein 1 isoform d
NM_001363035.1 NP_001349964.1 ADP-ribosylation factor GTPase-activating protein 1 isoform e
NM_001363036.1 NP_001349965.1 ADP-ribosylation factor GTPase-activating protein 1 isoform e
NM_001363037.1 NP_001349966.1 ADP-ribosylation factor GTPase-activating protein 1 isoform f
NM_001374670.1 NP_001361599.1 ADP-ribosylation factor GTPase-activating protein 1 isoform g
NM_145760.3 NP_665703.2 ADP-ribosylation factor GTPase-activating protein 1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22363216 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of endocytosis IDA
IDA: Inferred from direct assay
24792215 MGI
Cellular Component GO Annotation Evidence References Source
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
located in synapse IDA
IDA: Inferred from direct assay
22423108 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor GTPase-activating protein 1

  • ADP-ribosylation factor 1 GTPase activating protein

  • ARF GAP 1

  • ARF1 GAP

  • ARF1-directed GTPase-activating protein

Arfgap1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Arfgap1 Q9EPJ9 Lrrk2 Mus musculus Q5S006
Comigration in SDS
22363216
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12762 QS11 99.10% Unkown
HY-RS00899 ARFGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00901 ARFGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21984 Arfgap3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arfgap1 NCBI NCBI:55738