PALM3 - paralemmin 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 342979

About PALM3

This gene has 4 transcripts (splice variants), 1 gene allele, 104 orthologues and 3 paralogues. Biased expression in kidney (RPKM 13.7), liver (RPKM 6.5) and 10 other tissues.

Summary

Predicted to enable ATP binding activity. Involved in Toll signaling pathway; negative regulation of cytokine-mediated signaling pathway; and response to lipopolysaccharide. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PALM3 Products (2)

mRNA Protein Name
NM_001145028.2 NP_001138500.2 paralemmin-3 isoform 1
NM_001367327.1 NP_001354256.1 paralemmin-3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21187075 GOA
Biological Process GO Annotation Evidence References Source
involved in Toll signaling pathway IMP
IMP: Inferred from mutant phenotype
21187075 GOA
involved in negative regulation of cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
21187075 GOA
involved in response to lipopolysaccharide IDA
IDA: Inferred from direct assay
21187075 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paralemmin-3

Related Diseases

Diseases Alias
Median Neuropathy
Leopard Syndrome 1

  • LPRD1

  • Noonan Syndrome With Multiple Lentigines 1

  • Lentiginosis, Cardiomyopathic

  • Multiple Lentigines Syndrome

  • Leopard Syndrome, Type 1

  • Leopard Syndrome

  • Multiple Lentigines
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P10031 SAR441255 Agonist 99.84% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10932A pGk13a TFA 96.92% Unkown
HY-P0064 Palmitoyl Tetrapeptide-3 Inhibitor 99.18% Unkown
HY-P10031A SAR441255 TFA Agonist 99.93% Unkown
HY-P10380A palm11-PrRP31 TFA Agonist 99.44% Unkown
HY-P10379 palm-PrRP31 Agonist / Unkown
HY-P10380 palm11-PrRP31 Agonist / Unkown
HY-P10932 pGk13a / Unkown
HY-RS10007 PALM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PALM3 VGNC VGNC:44248
Rattus norvegicus PALM3 RGD RGD:2323602
Bos taurus PALM3 VGNC VGNC:32559
Mus musculus PALM3 MGD MGI:1921587
Others PALM3 NCBI