Xrcc5 - X-ray repair cross complementing 5 Gene

Also Known as Ku80; Kup80

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363247

Summary

Contributes to double-stranded DNA binding activity. Involved in several processes, including cellular hyperosmotic salinity response; cellular response to X-ray; and cellular response to fatty acid. Located in cytoplasm and nucleus. Part of protein-containing complex. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease and multiple myeloma. Orthologous to human XRCC5 (X-ray repair cross complementing 5). [provided by Alliance of Genome Resources, Apr 2022]

Xrcc5 Products (1)

mRNA Protein Name
NM_177419.3 NP_803154.2 X-ray repair cross-complementing protein 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to double-stranded DNA binding IDA
IDA: Inferred from direct assay
14576192 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14576192 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular hyperosmotic salinity response IDA
IDA: Inferred from direct assay
11175667 RGD
involved in cellular response to X-ray IDA
IDA: Inferred from direct assay
11966321 RGD
involved in cellular response to fatty acid IEP
IEP: Inferred from expression pattern
19180667 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17264098 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
14576192 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

X-ray repair cross-complementing protein 5

  • Ku autoantigen, 80kD)

  • X-ray repair complementing defective repair in Chinese hamster cells 5

  • X-ray repair cross complementation (double-strand-break rejoining

  • X-ray repair cross complementation (double-strand-break rejoining

  • Ku autoantigen, 80kD)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15900 XRCC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22924 Xrcc5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xrcc5 NCBI NCBI:7520